Yes. FreeBSD currently runs on the Intel x86 and the AMD64 architectures. The Intel EM64T, IA-64, ARM®, PowerPC®, and SPARC64® architectures are also supported. Upcoming platforms are MIPS® and S/390®, join the FreeBSD MIPS porting mailing list for more information about ongoing work on the MIPS platform. For general discussion on new architectures, join the FreeBSD non-Intel platforms porting mailing list.
If your machine has a different architecture and you need something right now, we suggest you look at NetBSD or OpenBSD.
Symmetric multi-processor (SMP) systems are generally supported by FreeBSD, although in some cases, BIOS or motherboard bugs may generate some problems.
FreeBSD will take advantage of HyperThreading (HTT) support on Intel CPUs that support this feature. A kernel with the options SMP feature enabled will automatically detect the additional logical processors.
smp(4) has more details.